Pet Safety / Products / Lily Ingestion and Feline Acute Renal Failure (Lilium and Hemerocallis Species — Easter, Tiger, Daylily, Asiatic — Unidentified Toxin, 100% Mortality Without Treatment)

Lily Ingestion and Feline Acute Renal Failure (Lilium and Hemerocallis Species — Easter, Tiger, Daylily, Asiatic — Unidentified Toxin, 100% Mortality Without Treatment) — pet safety profile

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True lilies (genus Lilium) and daylilies (genus Hemerocallis) cause acute renal tubular necrosis in cats with mortality approaching 100% if treatment is not initiated within 18 hours of exposure.

What is this product?

True lilies (genus Lilium) and daylilies (genus Hemerocallis) cause acute renal tubular necrosis in cats with mortality approaching 100% if treatment is not initiated within 18 hours of exposure. The toxic principle remains UNIDENTIFIED despite decades of investigation — multiple candidate fractions have been screened (steroidal glycoalkaloids, glycosaminoglycans) without definitive identification, which is why this product file references no specific compound hq_ids and the toxin(s) remain a Phase 56 SCI-14 enrichment candidate. ALL parts of the plant are toxic — petals, leaves, stamens, pollen, even the water from a vase containing lilies. As little as 2-3 leaves or one stamen ingestion causes acute renal tubular necrosis. ASPCA APCC ranks lily exposure in the top 10 feline plant-toxicity categories, with seasonal spikes around Easter (Lilium longiflorum, Easter lily) and Mother's Day (mixed-bouquet tiger and Asiatic lilies). Dogs are NOT affected by this specific renal toxicity (mild GI signs only) — the syndrome is feline-specific. Treatment requires aggressive intravenous fluid diuresis within 18 hours; delayed presentation yields anuric renal failure with mortality >90%. Prevention is absolute — keep all true lilies and daylilies out of cat households entirely; calla, peace, and peruvian lilies are botanically NOT in genus Lilium and do not cause this specific syndrome (though peace lily contains insoluble calcium oxalate crystals — a separate, milder oral irritation pattern).

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