Pet Safety / Compounds / Vinclozolin

Is Vinclozolin safe for dogs and cats?

Moderate risk for pets

Limited data; anti-androgenic effects expected in males at high exposure.

What is vinclozolin?

The IUPAC name is 3-(3,5-dichlorophenyl)-5-ethenyl-5-methyl-1,3-oxazolidine-2,4-dione.

Also known as: Ronilan, Vinclozoline, Ornalin, Vorlan.

IUPAC name
3-(3,5-dichlorophenyl)-5-ethenyl-5-methyl-1,3-oxazolidine-2,4-dione
CAS number
50471-44-8
Molecular formula
C12H9Cl2NO3
Molecular weight
286.11 g/mol
SMILES
CC1(OC(=O)N(C1=O)c1cc(Cl)cc(Cl)c1)C=C
PubChem CID
39676

Risk for dogs

Moderate risk

Limited data; anti-androgenic effects expected in males at high exposure.

Regulatory consensus

3 regulatory and scientific bodies have classified Vinclozolin. The classifications differ — that's the data.

AgencyYearClassificationNotes
EU2006Banned — endocrine disruptor (Reg 2006/1015/EC)
EPA2010Registrations voluntarily cancelled
TEDX2015Listed endocrine disruptor

Regulators apply different standards of evidence — animal-data weighting, exposure-pattern assumptions, epidemiological power thresholds — which is why two scientific bodies can review the same data and reach different conclusions. The disagreement is the data.

Where pets encounter vinclozolin

  • Agricultural

Safer alternatives

Lower-risk approaches that achieve a similar outcome to Vinclozolin:

  • Fludioxonil (non-endocrine-active fungicide)
    Trade-offs: Alternative fungicide or disease management strategy; spectrum of activity differs from original compound; resistance management considerations apply; integrated pest management approach recommended.
    Relative cost: 1.2-2×
  • Boscalid (SDHI fungicide)
    Trade-offs: Alternative fungicide or disease management strategy; spectrum of activity differs from original compound; resistance management considerations apply; integrated pest management approach recommended.
    Relative cost: 1.2-2×

Frequently asked questions

Is vinclozolin safe for pets?

Limited data; anti-androgenic effects expected in males at high exposure.

Why do regulators disagree about vinclozolin?

Vinclozolin has been classified by 3 agencies including EU, EPA, TEDX, with differing conclusions. Regulators apply different standards of evidence (animal data weighting, exposure-pattern assumptions, epidemiological power thresholds), which is why two scientific bodies can review the same data and reach different conclusions. See the regulatory consensus table on this page for the full picture.

See Vinclozolin in the pets app

Look up products containing vinclozolin, compare to alternatives, and explore the full data record.

Open in pets View raw API data

Sources (1)
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Reference data, not professional advice. Aggregates publicly available regulatory and scientific data; not a substitute for veterinary, medical, legal, or regulatory advice. Why we built ALETHEIA →