Pet Safety / Compounds / Thiacloprid

Is Thiacloprid safe for dogs and cats?

Low risk for pets

Not used in veterinary products; environmental contact from treated ornamentals and turf. Low acute mammalian toxicity; no specific dog health concerns at typical environmental exposures.

What is thiacloprid?

The IUPAC name is [3-[(6-chloro-3-pyridinyl)methyl]-1,3-thiazolidin-2-ylidene]cyanamide.

Also known as: [3-[(6-chloro-3-pyridinyl)methyl]-1,3-thiazolidin-2-ylidene]cyanamide, [3-[(6-chloropyridin-3-yl)methyl]-1,3-thiazolidin-2-ylidene]cyanamide, {3-[(6-chloropyridin-3-yl)methyl]-1,3-thiazolidin-2-ylidene}cyanamide, (3-((6-chloropyridin-3-yl)methyl)-1,3-thiazolidin-2-ylidene)cyanamide.

IUPAC name
[3-[(6-chloro-3-pyridinyl)methyl]-1,3-thiazolidin-2-ylidene]cyanamide
CAS number
111988-49-9
Molecular formula
C10H9ClN4S
Molecular weight
252.72 g/mol
SMILES
C1CSC(=NC#N)N1CC2=CN=C(C=C2)Cl
PubChem CID
115224

Risk for dogs

Low risk

Not used in veterinary products; environmental contact from treated ornamentals and turf. Low acute mammalian toxicity; no specific dog health concerns at typical environmental exposures.

Risk for cats

Low risk

Same low acute mammalian toxicity; no specific cat sensitivity. Environmental exposure through treated ornamentals in gardens is the primary contact route. No clinical toxicity expected at typical residue levels.

Regulatory consensus

2 regulatory and scientific bodies have classified Thiacloprid. The classifications differ — that's the data.

AgencyYearClassificationNotes
Multiple—Endocrine disruptor
EPA CTX / EPA OPP—Likely to be Carcinogenic to Humans

Regulators apply different standards of evidence — animal-data weighting, exposure-pattern assumptions, epidemiological power thresholds — which is why two scientific bodies can review the same data and reach different conclusions. The disagreement is the data.

Where pets encounter thiacloprid

  • Industrial Facilities — Manufacturing plants, Chemical storage areas, Waste treatment sites
  • Occupational Environments — Factories, Warehouses, Transportation vehicles

Safer alternatives

Lower-risk approaches that achieve a similar outcome to Thiacloprid:

  • Physical/mechanical pest control (IPM)
    Trade-offs: More labor-intensive. May not be sufficient for severe infestations.
    Relative cost: 1.2-2×

Frequently asked questions

Is thiacloprid safe for pets?

Not used in veterinary products; environmental contact from treated ornamentals and turf. Low acute mammalian toxicity; no specific dog health concerns at typical environmental exposures.

What products contain thiacloprid?

Thiacloprid appears in: Manufacturing plants (Industrial facilities); Chemical storage areas (Industrial facilities); Factories (Occupational environments); Warehouses (Occupational environments).

See Thiacloprid in the pets app

Look up products containing thiacloprid, compare to alternatives, and explore the full data record.

Open in pets View raw API data

Sources (2)
  1. US EPA: Neonicotinoid Registration Review — imidacloprid, clothianidin, thiamethoxam, acetamiprid, dinotefuran; bee risk assessment; sublethal effects; colony-level modeling; pollinator exposure through pollen and nectar; aquatic invertebrate toxicity; registration review decision (2020) (2020) — regulatory
  2. EFSA: Thiacloprid Peer Review — endocrine disruption; reproductive toxicity; rat carcinogenicity (liver adenoma, uterine tumors); hormonal mechanism; EU non-renewal of approval; Regulation (EU) 2020/23; comparison with other neonicotinoids (2019) (2019) — regulatory

Reference data, not professional advice. Aggregates publicly available regulatory and scientific data; not a substitute for veterinary, medical, legal, or regulatory advice. Why we built ALETHEIA →