Pet Safety / Compounds / Stannous fluoride

Is Stannous fluoride safe for dogs and cats?

High risk for pets

GHS Danger classification. Dogs lack metabolic pathways to detoxify many synthetic chemicals.

What is stannous fluoride?

The IUPAC name is difluorotin.

Also known as: difluorotin, Tin difluoride, Tin bifluoride, Tin Fluoride (SnF2).

IUPAC name
difluorotin
CAS number
7783-47-3
Molecular formula
F2Sn
Molecular weight
156.71 g/mol
SMILES
F[Sn]F
PubChem CID
24550

Risk for dogs

High risk

GHS Danger classification. Dogs lack metabolic pathways to detoxify many synthetic chemicals.

Risk for cats

High risk

GHS Danger classification. Cats lack metabolic pathways to detoxify many synthetic chemicals.

Regulatory consensus

1 regulatory bodyhas classified Stannous fluoride.

AgencyYearClassificationNotes
EPA CTX / Genetox—Genotoxicity: positive (Ames: positive, 29 positive / 37 negative reports)

Regulators apply different standards of evidence — animal-data weighting, exposure-pattern assumptions, epidemiological power thresholds — which is why two scientific bodies can review the same data and reach different conclusions. The disagreement is the data.

Where pets encounter stannous fluoride

  • Consumer Products — Toothpaste, Mouthwash, Dental products

Safer alternatives

Lower-risk approaches that achieve a similar outcome to Stannous fluoride:

  • Therapeutic alternatives (consult prescriber)
    Trade-offs: Drug-specific. Cannot substitute without medical guidance.
    Relative cost: 1.2-2×

Frequently asked questions

Is stannous fluoride safe for pets?

GHS Danger classification. Dogs lack metabolic pathways to detoxify many synthetic chemicals.

What products contain stannous fluoride?

Stannous fluoride appears in: Toothpaste (Consumer products); Mouthwash (Consumer products).

See Stannous fluoride in the pets app

Look up products containing stannous fluoride, compare to alternatives, and explore the full data record.

Open in pets View raw API data

Sources (3)
  1. PubChem Compound CID 24550 — database
  2. EPA CompTox Chemicals Dashboard — DTXSID6064822 — epa
  3. ATSDR Toxicological Profile — CAS 7783-47-3 — reference

Reference data, not professional advice. Aggregates publicly available regulatory and scientific data; not a substitute for veterinary, medical, legal, or regulatory advice. Why we built ALETHEIA →