Pet Safety / Compounds / Sodium monofluorophosphate

Is Sodium monofluorophosphate safe for dogs and cats?

Elevated risk for pets

GHS Warning classification. Dogs lack metabolic pathways to detoxify many synthetic chemicals.

What is sodium monofluorophosphate?

The IUPAC name is disodium;fluoro-dioxido-oxo-lambda5-phosphane.

Also known as: disodium;fluoro-dioxido-oxo-lambda5-phosphane, Phosphorofluoridic acid, disodium salt, Extra-Strength Aim, C810JCZ56Q.

IUPAC name
disodium;fluoro-dioxido-oxo-lambda5-phosphane
CAS number
10163-15-2
Molecular formula
FNa2O3P
Molecular weight
143.95 g/mol
SMILES
[Na+].[Na+].[O-]P([O-])(F)=O
PubChem CID
24266

Risk for dogs

Elevated risk

GHS Warning classification. Dogs lack metabolic pathways to detoxify many synthetic chemicals.

Risk for cats

Elevated risk

GHS Warning classification. Cats lack metabolic pathways to detoxify many synthetic chemicals.

Regulatory consensus

1 regulatory bodyhas classified Sodium monofluorophosphate.

AgencyYearClassificationNotes
EPA CTX / Genetox—Genotoxicity: negative (Ames: negative, 0 positive / 6 negative reports)

Regulators apply different standards of evidence — animal-data weighting, exposure-pattern assumptions, epidemiological power thresholds — which is why two scientific bodies can review the same data and reach different conclusions. The disagreement is the data.

Where pets encounter sodium monofluorophosphate

  • Consumer Products — Toothpaste, Dental products, Oral care

Safer alternatives

Lower-risk approaches that achieve a similar outcome to Sodium monofluorophosphate:

  • Therapeutic alternatives (consult prescriber)
    Trade-offs: Drug-specific. Cannot substitute without medical guidance.
    Relative cost: 1.2-2×

Frequently asked questions

Is sodium monofluorophosphate safe for pets?

GHS Warning classification. Dogs lack metabolic pathways to detoxify many synthetic chemicals.

What products contain sodium monofluorophosphate?

Sodium monofluorophosphate appears in: Toothpaste (Consumer products); Dental products (Consumer products).

See Sodium monofluorophosphate in the pets app

Look up products containing sodium monofluorophosphate, compare to alternatives, and explore the full data record.

Open in pets View raw API data

Sources (3)
  1. PubChem Compound CID 24266 — database
  2. EPA CompTox Chemicals Dashboard — DTXSID70872554 — epa
  3. ATSDR Toxicological Profile — CAS 10163-15-2 — reference

Reference data, not professional advice. Aggregates publicly available regulatory and scientific data; not a substitute for veterinary, medical, legal, or regulatory advice. Why we built ALETHEIA →