Pet Safety / Compounds / PFHpS (Perfluoroheptane sulfonic acid)

Is PFHpS (Perfluoroheptane sulfonic acid) safe for dogs and cats?

Moderate risk for pets

Dogs near AFFF sites show elevated PFHpS blood levels.

What is pfhps (perfluoroheptane sulfonic acid)?

The IUPAC name is 1,1,2,2,3,3,4,4,5,5,6,6,6-tridecafluorohexane-1-sulfonic acid.

Also known as: Perfluorohexanesulfonic acid, 355-46-4, 1,1,2,2,3,3,4,4,5,5,6,6,6-Tridecafluorohexane-1-sulfonic acid, Perfluorohexane-1-sulphonic acid.

IUPAC name
1,1,2,2,3,3,4,4,5,5,6,6,6-tridecafluorohexane-1-sulfonic acid
CAS number
375-92-8
Molecular formula
C6HF13O3S
Molecular weight
400.12 g/mol
SMILES
C(C(C(C(F)(F)S(=O)(=O)O)(F)F)(F)F)(C(C(F)(F)F)(F)F)(F)F
PubChem CID
67734

Risk for dogs

Moderate risk

Dogs near AFFF sites show elevated PFHpS blood levels.

Risk for cats

Moderate risk

Limited data but expected similar pharmacokinetics to PFHxS.

Regulatory consensus

2 regulatory and scientific bodies have classified PFHpS (Perfluoroheptane sulfonic acid). The classifications differ — that's the data.

AgencyYearClassificationNotes
EPA——
Stockholm Convention——Covered under PFOS listing as related substance

Regulators apply different standards of evidence — animal-data weighting, exposure-pattern assumptions, epidemiological power thresholds — which is why two scientific bodies can review the same data and reach different conclusions. The disagreement is the data.

Where pets encounter pfhps (perfluoroheptane sulfonic acid)

  • Drinking Water — AFFF-contaminated groundwater, Municipal water near military bases
    EPA UCMR5 analyte
  • Firefighting Foam — Legacy AFFF stockpiles, Training area runoff
    Component of legacy PFOS-based AFFF formulations

Safer alternatives

Lower-risk approaches that achieve a similar outcome to PFHpS (Perfluoroheptane sulfonic acid):

  • Fluorine-free firefighting foams (F3)
    Trade-offs: Functional performance and cost-effectiveness may vary by application.
    Relative cost: Lower (ingredient elimination)
  • Short-chain alternatives (though also persistent)
    Trade-offs: Functional performance and cost-effectiveness may vary by application.
    Relative cost: 1.2-2×

Frequently asked questions

Is pfhps (perfluoroheptane sulfonic acid) safe for pets?

Dogs near AFFF sites show elevated PFHpS blood levels.

What products contain pfhps (perfluoroheptane sulfonic acid)?

PFHpS (Perfluoroheptane sulfonic acid) appears in: AFFF-contaminated groundwater (drinking water); Municipal water near military bases (drinking water); Legacy AFFF stockpiles (firefighting foam); Training area runoff (firefighting foam).

See PFHpS (Perfluoroheptane sulfonic acid) in the pets app

Look up products containing pfhps (perfluoroheptane sulfonic acid), compare to alternatives, and explore the full data record.

Open in pets View raw API data

Sources (1)
  1. — expert_curation

Reference data, not professional advice. Aggregates publicly available regulatory and scientific data; not a substitute for veterinary, medical, legal, or regulatory advice. Why we built ALETHEIA →