Pet Safety / Compounds / N,N-Dimethyltryptamine (DMT)

Is N,N-Dimethyltryptamine (DMT) safe for dogs and cats?

Elevated risk for pets

Not veterinary or professional safety advice, and not a substitute for a veterinarian — consult one about your animal. Full disclaimer →

No veterinary use; ingestion of ayahuasca could cause serotonin syndrome, especially if on other serotonergic drugs.

What is n,n-dimethyltryptamine (dmt)?

The IUPAC name is 2-(1H-indol-3-yl)-N,N-dimethylethanamine.

Also known as: N,N-DIMETHYLTRYPTAMINE, DIMETHYLTRYPTAMINE, 2-(3-Indolyl)ethyldimethylamine, 3-(2-Dimethylaminoethyl)indole.

IUPAC name
2-(1H-indol-3-yl)-N,N-dimethylethanamine
CAS number
61-50-7
Molecular formula
C12H16N2
Molecular weight
188.27 g/mol
SMILES
CN(C)CCc1c[nH]c2ccccc12
PubChem CID
6089

Risk for dogs

Elevated risk

No veterinary use; ingestion of ayahuasca could cause serotonin syndrome, especially if on other serotonergic drugs.

Risk for cats

Elevated risk

More sensitive to serotonergic compounds than dogs. Any exposure is concerning.

Regulatory consensus

2 regulatory and scientific bodies have classified N,N-Dimethyltryptamine (DMT). The classifications differ — that's the data.

AgencyYearClassificationNotes
DEA1971Schedule I controlled substance
UN19711971 Convention — Schedule I (DMT itself; ayahuasca plants not scheduled)

Regulators apply different standards of evidence — animal-data weighting, exposure-pattern assumptions, epidemiological power thresholds — which is why two scientific bodies can review the same data and reach different conclusions. The disagreement is the data.

Where pets encounter n,n-dimethyltryptamine (dmt)

  • Natural Product
  • Illicit Drug

Safer alternatives

Lower-risk approaches that achieve a similar outcome to N,N-Dimethyltryptamine (DMT):

  • Ketamine (FDA-approved for depression)
    Trade-offs: Different mechanism (NMDA antagonist). FDA-approved (esketamine/Spravato). Dissociative rather than psychedelic. Abuse potential.
    Relative cost: $600-900/treatment session

Frequently asked questions

Is n,n-dimethyltryptamine (dmt) safe for pets?

No veterinary use; ingestion of ayahuasca could cause serotonin syndrome, especially if on other serotonergic drugs.

Why do regulators disagree about n,n-dimethyltryptamine (dmt)?

N,N-Dimethyltryptamine (DMT) has been classified by 2 agencies including DEA, UN, with differing conclusions. Regulators apply different standards of evidence (animal data weighting, exposure-pattern assumptions, epidemiological power thresholds), which is why two scientific bodies can review the same data and reach different conclusions. See the regulatory consensus table on this page for the full picture.

See N,N-Dimethyltryptamine (DMT) in the pets app

Look up products containing n,n-dimethyltryptamine (dmt), compare to alternatives, and explore the full data record.

Open in pets View raw API data

Sources (1)
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Reference data, not professional advice. Aggregates publicly available regulatory and scientific data; not a substitute for veterinary, medical, legal, or regulatory advice. Why we built ALETHEIA →