Is Maitotoxin safe for dogs and cats?
High risk for petsExtreme Ca2+ channel activation; cardiac failure at very low doses.
What is maitotoxin?
The IUPAC name is (2S)-2-[[(2S)-2-(dimethylamino)-3-methylbutanoyl]amino]-N-[(3R,4R)-3-methoxy-1-[(2S)-2-[(1R,2S)-1-methoxy-2-methyl-3-oxo-3-[[(1S)-2-phenyl-1-(1,3-thiazol-2-yl)ethyl]amino]propyl]pyrrolidin-1-yl]-5-methyl-1-oxoheptan-4-yl]-N,3-dimethylbutanamide.
Also known as: CHEMBL2111676.
- IUPAC name
- (2S)-2-[[(2S)-2-(dimethylamino)-3-methylbutanoyl]amino]-N-[(3R,4R)-3-methoxy-1-[(2S)-2-[(1R,2S)-1-methoxy-2-methyl-3-oxo-3-[[(1S)-2-phenyl-1-(1,3-thiazol-2-yl)ethyl]amino]propyl]pyrrolidin-1-yl]-5-methyl-1-oxoheptan-4-yl]-N,3-dimethylbutanamide
- CAS number
- 59392-53-9
- Molecular formula
- C164H256Na2O68S2
- Molecular weight
- 3425.86 g/mol
- SMILES
- CCC(C)C(C(CC(=O)N1CCCC1C(C(C)C(=O)NC(CC2=CC=CC=C2)C3=NC=CS3)OC)OC)N(C)C(=O)C(C(C)C)NC(=O)C(C(C)C)N(C)C
- PubChem CID
- 71459878
Risk for dogs
High riskExtreme Ca2+ channel activation; cardiac failure at very low doses.
Regulatory consensus
2 regulatory and scientific bodies have classified Maitotoxin. The classifications differ — that's the data.
| Agency | Year | Classification | Notes |
|---|---|---|---|
| FDA | 1995 | No specific regulation; falls under general seafood safety (21 CFR 123) | |
| WHO | 2020 | Recognized ciguatera toxin component; no formal MRL (analytical detection difficult) |
Regulators apply different standards of evidence — animal-data weighting, exposure-pattern assumptions, epidemiological power thresholds — which is why two scientific bodies can review the same data and reach different conclusions. The disagreement is the data.
Where pets encounter maitotoxin
- Marine Organism
Safer alternatives
Lower-risk approaches that achieve a similar outcome to Maitotoxin:
-
Ciguatera fish testing (rapid immunoassay kits)
Trade-offs: Detection, not substitution. False negative rate ~10-15%. Cannot detoxify contaminated fish.Relative cost: $5-25 per test
Frequently asked questions
Is maitotoxin safe for pets?
Extreme Ca2+ channel activation; cardiac failure at very low doses.
See Maitotoxin in the pets app
Look up products containing maitotoxin, compare to alternatives, and explore the full data record.
Open in pets View raw API dataSources (1)
- —
Reference data, not professional advice. Aggregates publicly available regulatory and scientific data; not a substitute for veterinary, medical, legal, or regulatory advice. Why we built ALETHEIA →