Pet Safety / Compounds / diPAP (Polyfluoroalkyl phosphate diester, 6:2/6:2)

Is diPAP (Polyfluoroalkyl phosphate diester, 6:2/6:2) safe for dogs and cats?

Moderate risk for pets

Limited exposure from pet food packaging.

What is dipap (polyfluoroalkyl phosphate diester, 6:2/6:2)?

The IUPAC name is bis(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl) hydrogen phosphate.

Also known as: Bis[2-(perfluorohexyl)ethyl] Phosphate, bis(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl) hydrogen phosphate, Bis(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluoro-1-octanol) hydrogen phosphate, DTXSID50561590.

IUPAC name
bis(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl) hydrogen phosphate
CAS number
57677-95-9
Molecular formula
C16H9F26O4P
Molecular weight
790.17 g/mol
SMILES
C(COP(=O)(O)OCCC(C(C(C(C(C(F)(F)F)(F)F)(F)F)(F)F)(F)F)(F)F)C(C(C(C(C(C(F)(F)F)(F)F)(F)F)(F)F)(F)F)(F)F
PubChem CID
14550408

Risk for dogs

Moderate risk

Limited exposure from pet food packaging.

Risk for cats

Moderate risk

Limited exposure data.

Regulatory consensus

3 regulatory and scientific bodies have classified diPAP (Polyfluoroalkyl phosphate diester, 6:2/6:2). The classifications differ — that's the data.

AgencyYearClassificationNotes
FDA——FDA revoked authorization for certain PFAS in food packaging in 2024
ECHA——
Denmark——Denmark banned PFAS in food packaging in 2020

Regulators apply different standards of evidence — animal-data weighting, exposure-pattern assumptions, epidemiological power thresholds — which is why two scientific bodies can review the same data and reach different conclusions. The disagreement is the data.

Where pets encounter dipap (polyfluoroalkyl phosphate diester, 6:2/6:2)

  • Food Packaging — Fast food wrappers, Microwave popcorn bags, Pizza boxes, Bakery bags
    Dominant PFAS in food-contact paper — detected in >50% of fast food packaging
  • House Dust — Household dust, Office dust
    Dust from treated textiles and carpets contains diPAPs
  • Human Biomonitoring — General population serum, Fast food workers
    Detected in human blood — dietary exposure from food packaging is primary route

Safer alternatives

Lower-risk approaches that achieve a similar outcome to diPAP (Polyfluoroalkyl phosphate diester, 6:2/6:2):

  • Plant-based grease barriers
    Trade-offs: Functional performance and cost-effectiveness may vary by application.
    Relative cost: 1.2-2×
  • Wax-coated paper
    Trade-offs: Functional performance and cost-effectiveness may vary by application.
    Relative cost: 1.2-2×
  • Bamboo fiber packaging
    Trade-offs: Functional performance and cost-effectiveness may vary by application.
    Relative cost: 1.2-2×
  • Silicone-coated paper
    Trade-offs: Functional performance and cost-effectiveness may vary by application.
    Relative cost: 1.2-2×

Frequently asked questions

Is dipap (polyfluoroalkyl phosphate diester, 6:2/6:2) safe for pets?

Limited exposure from pet food packaging.

What products contain dipap (polyfluoroalkyl phosphate diester, 6:2/6:2)?

diPAP (Polyfluoroalkyl phosphate diester, 6:2/6:2) appears in: Fast food wrappers (food packaging); Microwave popcorn bags (food packaging); Household dust (house dust); Office dust (house dust); General population serum (human biomonitoring).

See diPAP (Polyfluoroalkyl phosphate diester, 6:2/6:2) in the pets app

Look up products containing dipap (polyfluoroalkyl phosphate diester, 6:2/6:2), compare to alternatives, and explore the full data record.

Open in pets View raw API data

Sources (1)
  1. — expert_curation

Reference data, not professional advice. Aggregates publicly available regulatory and scientific data; not a substitute for veterinary, medical, legal, or regulatory advice. Why we built ALETHEIA →