Pet Safety / Compounds / DEET (N,N-Diethyl-meta-toluamide)

Is DEET (N,N-Diethyl-meta-toluamide) safe for dogs and cats?

Low risk for pets

DEET products formulated for humans should not be applied directly to dogs, but incidental exposure is low risk.

What is deet (n,n-diethyl-meta-toluamide)?

DEET (N,N-Diethyl-meta-toluamide) is a insect repellent, amide, aromatic compound.

The IUPAC name is N,N-diethyl-3-methylbenzamide.

Also known as: DEET, N,N-Diethyl-meta-toluamide, N,N-Diethyl-3-methylbenzamide, m-DET.

IUPAC name
N,N-diethyl-3-methylbenzamide
CAS number
134-62-3
Molecular formula
C12H17NO
Molecular weight
191.27 g/mol
SMILES
CCN(CC)C(=O)C1=CC(C)=CC=C1
PubChem CID
4284

Risk for dogs

Low risk

DEET products formulated for humans should not be applied directly to dogs, but incidental exposure is low risk.

Veterinary toxicology references indicate DEET has moderate toxicity in dogs if ingested in large amounts. Incidental dermal exposure is generally well-tolerated. Dedicated veterinary insect repellent products are preferred for dogs.

What to do: Do not apply human DEET products to dogs. Use veterinary-approved repellents. Contact veterinarian if ingestion occurs.

Risk for cats

Context-dependent

Generally considered safer for cats than permethrin, but not recommended for direct application. Cats may be more sensitive due to glucuronidation deficiency.

While DEET is not in the same high-toxicity category as permethrin for cats, felines have reduced hepatic glucuronidation capacity. Veterinary-approved products should be used instead of human DEET products.

What to do: Do not apply DEET products to cats. Use veterinary-approved feline-safe repellents. Contact veterinarian if exposure occurs.

Regulatory consensus

4 regulatory and scientific bodies have classified DEET (N,N-Diethyl-meta-toluamide). The classifications differ — that's the data.

AgencyYearClassificationNotes
US EPA2014Registered pesticide (active ingredient in insect repellents)Re-registered 2014; considered safe when used as directed
WHORecommended for malaria preventionWHO recommends DEET-based repellents for personal protection against vector-borne diseases
CDCRecommended insect repellentCDC recommends DEET along with picaridin, IR3535, and OLE as effective repellents
EU BPRApproved biocidal active substance (PT19 — Repellents and attractants)Approved under EU Biocidal Products Regulation

Regulators apply different standards of evidence — animal-data weighting, exposure-pattern assumptions, epidemiological power thresholds — which is why two scientific bodies can review the same data and reach different conclusions. The disagreement is the data.

Where pets encounter deet (n,n-diethyl-meta-toluamide)

  • Insect Repellent SprayOFF! Deep Woods, Cutter Backwoods, Repel 100
  • Insect Repellent LotionOFF! FamilyCare, Ultrathon
  • Treated ClothingMilitary BDU treated uniforms, insect repellent wristbands

Safer alternatives

Lower-risk approaches that achieve a similar outcome to DEET (N,N-Diethyl-meta-toluamide):

  • Picaridin (Icaridin)
  • Oil of Lemon Eucalyptus (OLE/PMD)
  • IR3535

Frequently asked questions

Is deet (n,n-diethyl-meta-toluamide) safe for pets?

DEET products formulated for humans should not be applied directly to dogs, but incidental exposure is low risk.

What products contain deet (n,n-diethyl-meta-toluamide)?

DEET (N,N-Diethyl-meta-toluamide) appears in: OFF! Deep Woods (insect repellent spray); Cutter Backwoods (insect repellent spray); OFF! FamilyCare (insect repellent lotion); Ultrathon (insect repellent lotion); Military BDU treated uniforms (treated clothing).

What should I do if my pet is exposed to deet (n,n-diethyl-meta-toluamide)?

Do not apply human DEET products to dogs. Use veterinary-approved repellents. Contact veterinarian if ingestion occurs.

Why do regulators disagree about deet (n,n-diethyl-meta-toluamide)?

DEET (N,N-Diethyl-meta-toluamide) has been classified by 4 agencies including US EPA, WHO, CDC, EU BPR, with differing conclusions. Regulators apply different standards of evidence (animal data weighting, exposure-pattern assumptions, epidemiological power thresholds), which is why two scientific bodies can review the same data and reach different conclusions. See the regulatory consensus table on this page for the full picture.

See DEET (N,N-Diethyl-meta-toluamide) in the pets app

Look up products containing deet (n,n-diethyl-meta-toluamide), compare to alternatives, and explore the full data record.

Open in pets View raw API data

Sources (6)

  1. — regulatory
  2. — reference_database
  3. — clinical_guidance
  4. — clinical_guidance
  5. — veterinary
  6. — expert_curation

Reference data, not professional advice. Aggregates publicly available regulatory and scientific data; not a substitute for veterinary, medical, legal, or regulatory advice. Why we built ALETHEIA →