Pet Safety / Compounds / DDT (dichlorodiphenyltrichloroethane)

Is DDT (dichlorodiphenyltrichloroethane) safe for dogs and cats?

Moderate risk for pets

Bioaccumulates in adipose; impaired neurological function at high doses.

What is ddt (dichlorodiphenyltrichloroethane)?

The IUPAC name is 1-chloro-4-[2,2,2-trichloro-1-(4-chlorophenyl)ethyl]benzene.

Also known as: 1-chloro-4-[2,2,2-trichloro-1-(4-chlorophenyl)ethyl]benzene, 1-Chloro-4-(2,2,2-trichloro-1-(4-chlorophenyl)ethyl)benzene, RefChem:127031, Clofenotane.

IUPAC name
1-chloro-4-[2,2,2-trichloro-1-(4-chlorophenyl)ethyl]benzene
CAS number
50-29-3
Molecular formula
C14H9Cl5
Molecular weight
354.5 g/mol
SMILES
C1=CC(=CC=C1C(C2=CC=C(C=C2)Cl)C(Cl)(Cl)Cl)Cl
PubChem CID
3036

Risk for dogs

Moderate risk

Bioaccumulates in adipose; impaired neurological function at high doses.

Risk for cats

Moderate risk

Similar bioaccumulation; avoid near agricultural application areas.

Regulatory consensus

11 regulatory and scientific bodies have classified DDT (dichlorodiphenyltrichloroethane). The classifications differ — that's the data.

AgencyYearClassificationNotes
IARC2015Group 2A (probably carcinogenic to humans)Breast cancer, NHL; Monograph 113; reclassified from 2B
US EPA1987Likely to be carcinogenic to humansLiver tumors; banned US 1972; still globally used for malaria control
EPA CTX / IRISB2 (Probable human carcinogen - based on sufficient evidence of carcinogenicity in animals)
EPA CTX / NTP RoCReasonably Anticipated to be a Human Carcinogen
EPA CTX / IARCGroup 2A - Probably carcinogenic to humans
EPA CTX / EPA OPPGroup B2 Probable Human Carcinogen
EPA CTX / CalEPAKnown human carcinogen
EPA CTX / GenetoxGenotoxicity: negative (Ames: negative, 4 positive / 6 negative reports)
EPA CTX / GenetoxGenotoxicity: negative (Ames: negative, 4 positive / 6 negative reports)
EPA CTX / Skin-EyeEye Irritation: Category 2B (score: moderate)
EPA CTX / Skin-EyeSkin Irritation: Not classified (score: low)

Regulators apply different standards of evidence — animal-data weighting, exposure-pattern assumptions, epidemiological power thresholds — which is why two scientific bodies can review the same data and reach different conclusions. The disagreement is the data.

Where pets encounter ddt (dichlorodiphenyltrichloroethane)

  • Industrial FacilitiesManufacturing plants, Chemical storage areas, Waste treatment sites
  • Occupational EnvironmentsFactories, Warehouses, Transportation vehicles

Safer alternatives

Lower-risk approaches that achieve a similar outcome to DDT (dichlorodiphenyltrichloroethane):

  • Physical/mechanical pest control (IPM)
    Trade-offs: More labor-intensive. May not be sufficient for severe infestations.
    Relative cost: Variable; lower long-term

Frequently asked questions

Is ddt (dichlorodiphenyltrichloroethane) safe for pets?

Bioaccumulates in adipose; impaired neurological function at high doses.

What products contain ddt (dichlorodiphenyltrichloroethane)?

DDT (dichlorodiphenyltrichloroethane) appears in: Manufacturing plants (Industrial facilities); Chemical storage areas (Industrial facilities); Factories (Occupational environments); Warehouses (Occupational environments).

Why do regulators disagree about ddt (dichlorodiphenyltrichloroethane)?

DDT (dichlorodiphenyltrichloroethane) has been classified by 11 agencies including IARC, US EPA, EPA CTX / IRIS, EPA CTX / NTP RoC, EPA CTX / IARC, with differing conclusions. Regulators apply different standards of evidence (animal data weighting, exposure-pattern assumptions, epidemiological power thresholds), which is why two scientific bodies can review the same data and reach different conclusions. See the regulatory consensus table on this page for the full picture.

See DDT (dichlorodiphenyltrichloroethane) in the pets app

Look up products containing ddt (dichlorodiphenyltrichloroethane), compare to alternatives, and explore the full data record.

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Sources (2)

  1. IARC Monographs Volume 113: DDT, Lindane, and 2,4-D (2015) — regulatory
  2. US EPA: DDT — A Brief History and Status (1987) — regulatory

Reference data, not professional advice. Aggregates publicly available regulatory and scientific data; not a substitute for veterinary, medical, legal, or regulatory advice. Why we built ALETHEIA →