Pet Safety / Compounds / Acetamiprid

Is Acetamiprid safe for dogs and cats?

Low risk for pets

Not used in veterinary products; environmental exposure through treated ornamentals, vegetables, and turf. Low acute mammalian toxicity; no specific dog toxicity concerns at typical environmental exposures.

What is acetamiprid?

The IUPAC name is N-[(6-chloro-3-pyridinyl)methyl]-N'-cyano-N-methylethanimidamide.

Also known as: N-[(6-chloro-3-pyridinyl)methyl]-N'-cyano-N-methylethanimidamide, N-((6-Chloro-3-pyridinyl)methyl)-N'-cyano-N-methylethanimidamide, RefChem:1090707, DTXCID8014300.

IUPAC name
N-[(6-chloro-3-pyridinyl)methyl]-N'-cyano-N-methylethanimidamide
CAS number
135410-20-7
Molecular formula
C10H11ClN4
Molecular weight
222.67 g/mol
SMILES
CC(=NC#N)N(C)CC1=CN=C(C=C1)Cl
PubChem CID
213021

Risk for dogs

Low risk

Not used in veterinary products; environmental exposure through treated ornamentals, vegetables, and turf. Low acute mammalian toxicity; no specific dog toxicity concerns at typical environmental exposures.

Risk for cats

Low risk

Not used in cat products; same low mammalian toxicity as for dogs. Cats in gardens with acetamiprid-treated ornamentals or vegetables may have incidental exposure; no clinically significant toxicity expected at typical residue concentrations.

Regulatory consensus

1 regulatory bodyhas classified Acetamiprid.

AgencyYearClassificationNotes
EPA CTX / EPA OPP—Not Likely to Be Carcinogenic in Humans

Regulators apply different standards of evidence — animal-data weighting, exposure-pattern assumptions, epidemiological power thresholds — which is why two scientific bodies can review the same data and reach different conclusions. The disagreement is the data.

Where pets encounter acetamiprid

  • Industrial Facilities — Manufacturing plants, Chemical storage areas, Waste treatment sites
  • Occupational Environments — Factories, Warehouses, Transportation vehicles

Safer alternatives

Lower-risk approaches that achieve a similar outcome to Acetamiprid:

  • Physical/mechanical pest control (IPM)
    Trade-offs: More labor-intensive. May not be sufficient for severe infestations.
    Relative cost: 1.2-2×

Frequently asked questions

Is acetamiprid safe for pets?

Not used in veterinary products; environmental exposure through treated ornamentals, vegetables, and turf. Low acute mammalian toxicity; no specific dog toxicity concerns at typical environmental exposures.

What products contain acetamiprid?

Acetamiprid appears in: Manufacturing plants (Industrial facilities); Chemical storage areas (Industrial facilities); Factories (Occupational environments); Warehouses (Occupational environments).

See Acetamiprid in the pets app

Look up products containing acetamiprid, compare to alternatives, and explore the full data record.

Open in pets View raw API data

Sources (2)
  1. US EPA: Neonicotinoid Registration Review — imidacloprid, clothianidin, thiamethoxam, acetamiprid, dinotefuran; bee risk assessment; sublethal effects; colony-level modeling; pollinator exposure through pollen and nectar; aquatic invertebrate toxicity; registration review decision (2020) (2020) — regulatory
  2. EFSA: Acetamiprid Peer Review — human health; developmental neurotoxicity; dietary exposure; bee risk under new guidance document; MRL review; EU registration status (2023) (2023) — regulatory

Reference data, not professional advice. Aggregates publicly available regulatory and scientific data; not a substitute for veterinary, medical, legal, or regulatory advice. Why we built ALETHEIA →